Eirini Kaiserli Research Group

Eirini Kaiserli (PI) was born and educated on the island of Kos, Greece and became interested in Plant Biology and Photobiology during her Undergraduate degree at the University of Glasgow, UK. One of the most defining points in her academic path was the award of the Sainsbury Undergraduate Studentship from the Gatsby Foundation to work at one of the leading Plant Photobiology labs at Carnegie Institution of Washington at Stanford University in California. This research experience inspired her to pursue a PhD on “UV-B perception” at the lab of Professor Gareth I Jenkins at the University of Glasgow, UK followed by a Human Frontier Science Program post-doctoral fellowship on “Light signal integration” at the lab of Professor Joanne Chory, an inspiring Woman in Science role model and Howard Hughes Medical Investigator at the Salk Institute in San Diego, California. Eirini joined the School of Molecular Biosciences at the University of Glasgow to start her research group as a Lord Kelvin Adam Smith Fellow in 2013, received tenure in 2016 and was promoted to Senior Lecturer (Associate Professor) in 2019, just before the onset of her maternity leave. In addition to directing a research group, Eirini delivers lectures, tutorials, lab classes, supervises and mentors undergraduate and postgraduate students on subjects related to Molecular, Cellular and Plant Biology. Eirini is a Gatsby Plant Science Advisor and Mentor, a member of internal and external professional committees, editorial boards and mentoring schemes and promotes knowledge exchange by participating and organising international conferences and science communication events.

The Kaiserli lab has been fortunate to host and train very talented and enthusiastic early career researchers from diverse backgrounds that have contributed to the cultural and scientific diversity of the Plant Science Group and the University of Glasgow. Our lab aims to promote collegiality, research integrity, collaboration and career progression. Our research focuses on investigating “How light and temperature control plant growth and development at the chromatin level”.

People

Kaiserli lab group

Dr Eirini Kaiserli

Associate Professor

Lord Kelvin Adam Smith Fellow, University of Glasgow, UK

Human Frontier Science Post-doctoral Fellow, The Salk Insitute, La Jolla, USA

PhD University of Glasgow, UK

MSci University of Glasgow, UK

Gatsby Undergraduate Studentship, Carnegie Institution of Washington, Stanford, USA

Dr Anna Zioutopoulou

Post-doctoral Researcher

PhD University of Glasgow, UK

MScR University of Glasgow, UK

MSci BSc Hons University of Ioannina, Greece

Erasmus+ internship University of Glasgow, UK

Dr Elisa Vellutini

Research Assistant

PhD University of Glasgow, UK

MSc University of Pisa, Italy

Erasmus+ University of Glasgow, UK

BSc University of Pisa, Italy

Yuyang Li

Research Assistant

MSc University of Glasgow, UK

BSc Southern University of Science & Technology, China

Tianyuan Xu

PhD

MScR University of Birmingham

BSc Xinjiang Agricultural University, China

Internship Nanjing Agricultural University, China

Eirini Patitaki

MVLS PhD Scholarship

MSc University of Glasgow, UK

BSc Southern University of Science & Technology, China

Bochen Liu

CSC PhD Scholarship

MScR Northwest A & F University, Shaanxi, China

BSc Shandong Agricultural University, Shandong, China

Natalia Apostolopoulou

PhD Student

Co-supervised with Sofie Spatharis

Research

• Transcriptional and epigenetic regulation of gene expression by light & temperature

• Photomorphogenesis and photoperiodic flowering in Arabidopsis

• Light-induced changes in nuclear architecture

• Subnuclear condensate structure and function

Plants exhibit enormous plasticity, therefore they provide a great model for studying how cells and organisms respond and adapt to the constantly changing environment. Light is an environmental stimulus essential not only for energy production, but also for triggering a plethora of developmental and photoprotective responses. The majority of light signalling components are constitutively localised or translocated into the nucleus and form subnuclear structures, also referred to as nuclear foci, photobodies or speckles to regulate gene expression, protein modification and DNA repair. Studies in animal systems indicate a direct correlation between the disruption of nuclear microdomains and the onset of heritable diseases, ageing and cancer. New findings in this area could have major applications in healthcare, agricultural sustainability and basic biosciences.

The focus of my research is to understand how environmental stimuli influence the organization of the plant nucleus, and how this translates into changes in cell and plant architecture and development. In particular, my lab is interested in elucidating the functional significance and regulation of nuclear bodies in response to light and temperature. Identification and characterisation of novel components that bridge light signalling to protein stability, transcriptional regulation or DNA damage repair will provide better understanding of the role of photobody formation in plant growth, development and photoprotection.

In order to monitor the dynamic nature, the speed of formation, the identity and the composition of these structures within the nucleus, my lab is employing a multidisciplinary approach using genomics, proteomics and cell biology.

Produced with BioRender

Produced with BioRender

Funders

Resources

Plantae Blog

Plant photoreceptors; detecting & reacting to light – Eirini Kaiserli

#UKPlantSciPresents webinar:Eirini Kaiserli discusses her research on regulation of light signaling.

CA19125 – EPIgenetic mechanisms of Crop Adaptation To Climate cHange (EPI-CATCH)

Alumni

Former Kaiserli Lab Members

  • Katalin Paldi (PGR) 2014-15, M.Res Plant Science, University of Glasgow, current position: Postdoc at University of Florida, USA
  • Jonna Aitta (UG) 2014-15, University of Glasgow
  • Egle Begaite (UG) 2014-15 Dobbie Smith Awardee, University of Glasgow
  • Matthew Habasque (UG) 2015, Summer Internship, University of Glasgow
  • Alice Robustelli-Test (PGR) 2015, Erasmus +, University of Milan
  • Rosa Maria Castillo Bravo (PGR) 2015-16, Erasmus +, University of Seville, Current position: PhD student at the University of Galway, Ireland
  • Adam Gauley (UG) 2015-16, MCB Honours Project, University of Glasgow, Current position: PhD student at JIC, Norwich
  • Giovanni Giuriani (UG) 2016, Summer Internship, University of Glasgow, Current position: PhD at the University of Glasgow
  • Silviya Dimova (UG) 2016-17, Genetics Honours Project, University of Glasgow
  • Jennifer Fleming (UG) 2016-17, Genetics Honours Project, University of Glasgow
  • Justin Joseph (PGT) 2016-17, MRes Biomedical Sciences, University of Glasgow
  • Mihail Peychev (PGT) 2016-17, MRes Biomedical Sciences, University of Glasgow
  • Gabriela Krawiec (UG), Lab volunteer, 2016-17, University of Glasgow
  • Tajra Lulo (UG), Summer Visiting Internship, 2017, International University of Sarajevo, Bosnia
  • Catriona MacIntosh (UG), Summer Internship, 2017, Genetics, University of Glasgow
  • Elisa Vellutini (PGR) 2017-18, Erasmus +, University of Pisa, IT
  • Maisoun Alalami (UG), 2017-18, Genetics Honours Project, University of Glasgow
  • Michalis Giovanakis (UG), 2017-2018, Erasmus +, University of Crete, GR
  • William MacIntosh-Smith (2018) MRes Medical Genetics, University of Glasgow
  • Giorgio Perrella, Postdoc (2016-2019), Current Position: Assistant Professor, University of Milan, Italy
  • Jack Bunyan, UG (2018-2019)
  • Samantha Weslee Rosenbaum, MSc (2019), University of Glasgow
  • Lilian Umekunne, MSc (2019), University of Glasgow
  • Ruben Tesoro-Moreno, UG (2021-2022), Current Position: PhD at EMBL, Heidelberg, Germany
  • Mhairi Davidson, PhD (2016-2020), Current Position: Postdoc at ENS, Paris, France
  • Eirini Patitaki, Erasmus + (2017), MScR (2019-2020)
  • Liz O’ Donnell, Technician (2013-2020)
  • Yuyang Li (2022), MSc University of Glasgow
  • Weiwei Fang, PhD (2018-2022), Current Position: Postdoc at the University of Milan, Italy
  • Anna Zioutopoulou, Erasmus + (2016), MScRes (2017-2018), PhD (2018-2023)
  • Jakub Michalski, UG (2022-2023)
  • Maria Valverde Caba, UG (2022-2023), Current Position: MSc in Bioinformatics, University of Glasgow
  • Micaela Milani, MSci (2022-2023), University of Glasgow
  • Achilleas Panteli, MSc (2022-2023), University of Glasgow
  • Miriam Negussu, Visiting PhD scholar, University of Florence